|
Positions of the named susceptibility loci from murine genome studies involving NZB, NZW, NZM2410, BXSB, and MRL/lpr mice (Wakeland et al, 1999) [2]. |
|
| Chromosome |
|
| location |
Susceptibility loci |
|
|
|
| 1 |
Bxs1, Bxs2, Sbw1, Gld, Sle1, Nba2, Lbw7, Bxs3 |
| 3 |
Sles3* |
| 4 |
Sle2, Sbw2, Lbm1, nba1, Lbw2, Lmb1, Sles2* |
| 5 |
Sle6, Lmb2, Lbw3 |
| 6 |
Lbw4 |
| 7 |
Lrdm1, Sle5, Sle3, Lbw5, Lmb3, Nba3 |
| 9 |
Sles4* |
| 10 |
Lmb4 |
| 11 |
Lbw8 |
| 12 |
Lrdm2 |
| 17 |
H2d/z, Sle4, Sles1* |
| 18 |
Lbw6 |
| 19 |
Fas |
|
*Suppressive modifiers, responsible for the suppression of fatal disease in the NZW genome. | |
Ahmad and Bruce Arthritis Res 2001 3:331 doi:10.1186/ar324 |
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