Table 1

Positions of the named susceptibility loci from murine genome studies involving NZB, NZW, NZM2410, BXSB, and MRL/lpr mice (Wakeland et al, 1999) [2].

Chromosome

location
Susceptibility loci

1
Bxs1, Bxs2, Sbw1, Gld, Sle1, Nba2, Lbw7, Bxs3
3
Sles3*
4
Sle2, Sbw2, Lbm1, nba1, Lbw2, Lmb1, Sles2*
5
Sle6, Lmb2, Lbw3
6
Lbw4
7
Lrdm1, Sle5, Sle3, Lbw5, Lmb3, Nba3
9
Sles4*
10
Lmb4
11
Lbw8
12
Lrdm2
17
H2d/z, Sle4, Sles1*
18
Lbw6
19
Fas

*Suppressive modifiers, responsible for the suppression of fatal disease in the NZW genome.

Ahmad and Bruce Arthritis Res 2001 3:331   doi:10.1186/ar324