Table 1

Camptothecin does not affect fibroblast viability

Cell number


CPT concentration (mol/l)

NS

SD


None (controls)

5904 ± 731

5928 ± 1081

10-9

5614 ± 818

6166 ± 1120

10-8

5424 ± 720

5368 ± 1046

10-7

5051 ± 770

5785 ± 1203

10-6

5142 ± 801

5711 ± 1351


Confluent fibroblasts after 48 h treatment with indicated doses of CPT were trypsinized and cell number was the mean of two counts using a Coulter counter. Values are mean cell numbers ± SEM from five SSc and healthy control pairs after treatment with CPT. CPT = camptothecin; NS, normal fibroblasts; SD, SSc fibroblasts.

Czuwara-Ladykowska et al. Arthritis Res 2001 3:311-318   doi:10.1186/ar321

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