|
Camptothecin does not affect fibroblast viability |
||
| Cell number |
||
|
|
||
| CPT concentration (mol/l) |
NS |
SD |
|
|
||
| None (controls) |
5904 ± 731 |
5928 ± 1081 |
| 10-9 |
5614 ± 818 |
6166 ± 1120 |
| 10-8 |
5424 ± 720 |
5368 ± 1046 |
| 10-7 |
5051 ± 770 |
5785 ± 1203 |
| 10-6 |
5142 ± 801 |
5711 ± 1351 |
|
Confluent fibroblasts after 48 h treatment with indicated doses of CPT were trypsinized and cell number was the mean of two counts using a Coulter counter. Values are mean cell numbers ± SEM from five SSc and healthy control pairs after treatment with CPT. CPT = camptothecin; NS, normal fibroblasts; SD, SSc fibroblasts. | ||
Czuwara-Ladykowska et al. Arthritis Res 2001 3:311 doi:10.1186/ar321 |
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