Abstract

A new alkaline phosphotungstate reduction reaction is introduced in a simple procedure for the determination of the total urate-equivalent chromogens (TUEC) for the first time in serum, aiming that these substances will receive a renewed and well deserved attention.

The linear regression equation : Y = 0.0185 + 0.21159 X, the correlation coefficient, r = 0.9975, S_y.x = 0.0075. The Cv_s ranged from 0.23 to 2.4% over a concentration range from 2.513 to 4.995 mmol/L. The mean value of TUEC in 18 males was calculated as 3.235 mmol/L, compared to a value of 2.545 mmol/L obtained as the mean TUEC in 18 non-pregnant women.