Table 2

Expression of bradykinin 1 and bradykinin 2 receptors in DRGs L1–L5

Percentage of labelled neurons

Experimental group

Test site

BK–gold

BK–gold + BK1 agonist

BK–gold + BK2 agonist

Untreated control animals

i.l.

38.8 ± 7.0

38.0 ± 2.4

0

c.l.

40.4 ± 0.9

41.6 ± 4.6

1.2 ± 1.8

Immunized rats without knee injection

i.l.

42.0 ± 1.4

38.8 ± 2.3

0

c.l.

41.6 ± 5.2

38.8 ± 6.1

0

Rats at 3 days of AIA

i.l.

77.0 ± 3.4

83.4 ± 2.9

0.4 ± 0.9

c.l.

88.0 ± 4.7

88.0 ± 4.7

1.6 ± 2.1

Rats at 42 days of AIA

i.l.

74.8 ± 4.8

71.6 ± 8.9

0.4 ± 0.9

c.l.

38.8 ± 2.3

38.0 ± 2.5

1.6 ± 3.6

Values shown are the means and standard deviations. Abbreviations: i.l., ipsilateral to injected knee; c.l., contralateral to injected knee.

von Banchet et al. Arthritis Res 2000 2:424   doi:10.1186/ar121