Arthritis Research & Therapy

official impact factor 4.36

Fibroblast biology: Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis

Thomas Pap, Ulf Müller-Ladner, Renate E Gay and Steffen Gay

Arthritis Res 2000, 2:361-367 doi:10.1186/ar113

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BioMed Central: 20 citations

Research article   Open Access

Identification and evaluation of novel synovial tissue biomarkers in rheumatoid arthritis by laser scanning cytometry

Christiane Fueldner, Anja Mittag, Jens Knauer, Maria Biskop, Pierre Hepp, Roger Scholz, Ulf Wagner, Ulrich Sack, Frank Emmrich, Attila Tárnok, Joerg Lehmann Arthritis Research & Therapy 2012, 14:R8 (17 January 2012)

Research   Open Access

Initiation but no execution - modulation of peripheral blood lymphocyte apoptosis in rheumatoid arthritis - a potential role for heat shock protein 70

Devapregasan Moodley, Girish M Mody, Anil A Chuturgoon Journal of Inflammation 2011, 8:30 (3 November 2011)

Research article   Open Access

High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts

Heidi Wähämaa, Hanna Schierbeck, Hulda S Hreggvidsdottir, Karin Palmblad, Anne-Charlotte Aveberger, Ulf Andersson, Helena Harris Arthritis Research & Therapy 2011, 13:R136 (26 August 2011)

Research article   Open Access

In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage

David Pretzel, Dirk Pohlers, Sönke Weinert, Raimund W Kinne Arthritis Research & Therapy 2009, 11:R25 (18 February 2009)

Research article   Open Access

Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent

Noreen Pundt, Marvin A Peters, Christina Wunrau, Simon Strietholt, Carsten Fehrmann, Katja Neugebauer, Christine Seyfert, Frans van Valen, Thomas Pap, Ingmar Meinecke Arthritis Research & Therapy 2009, 11:R16 (5 February 2009)

Research article   Open Access

MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis

Jinah Jang, Dae-Seog Lim, Young-Eun Choi, Yong Jeong, Seung-Ah Yoo, Wan-Uk Kim, Yong-Soo Bae Arthritis Research & Therapy 2006, 8:R170 (14 November 2006)

Research article   Open Access Highly Accessed

Local treatment with the selective IκB kinase β inhibitor NEMO-binding domain peptide ameliorates synovial inflammation

Sander W Tas, Margriet J Vervoordeldonk, Najat Hajji, Michael J May, Sankar Ghosh, Paul P Tak Arthritis Research & Therapy 2006, 8:R86 (9 May 2006)

Local small peptide inhibition of a key regulator of synovial inflammation improves established arthritis in an animal model and also prevents pro-inflammatory cytokine production in human rheumatoid arthritis synovial biopsies.

Research article   Open Access Highly Accessed

The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis

Pnina Fishman, Sara Bar-Yehuda, Lea Madi, Lea Rath-Wolfson, Avivit Ochaion, Shira Cohen, Ehud Baharav Arthritis Research & Therapy 2006, 8:R33 (13 January 2006)

Commentary   Free

Rheumatoid arthritis as a hyper-endoplasmic reticulum-associated degradation disease

Satoshi Yamasaki, Naoko Yagishita, Kaneyuki Tsuchimochi, Kusuki Nishioka, Toshihiro Nakajima Arthritis Research & Therapy 2005, 7:181-186 (17 August 2005)

Commentary   Free

MAPK signalling in rheumatoid joint destruction: can we unravel the puzzle?

Lars-Henrik Meyer, Thomas Pap Arthritis Research & Therapy 2005, 7:177-178 (16 August 2005)

Research article   Open Access

Expression of CD147 on monocytes/macrophages in rheumatoid arthritis: its potential role in monocyte accumulation and matrix metalloproteinase production

Ping Zhu, Jin Ding, Jun Zhou, Wei-Jia Dong, Chun-Mei Fan, Zhi-Nan Chen Arthritis Research & Therapy 2005, 7:R1023-R1033 (23 June 2005)

Research article   Open Access Highly Accessed

Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin

Karim Raza, Francesco Falciani, S John Curnow, Emma J Ross, Chi-Yeung Lee, Arne N Akbar, Janet M Lord, Caroline Gordon, Christopher D Buckley, Mike Salmon Arthritis Research & Therapy 2005, 7:R784-R795 (7 April 2005)

Patients with early arthritis who subsequently develop rheumatoid arthritis (RA) have a distinct but transient synovial fluid cytokine profile. This not only gives clues about the pathology of RA, but also has potential for use as a diagnostic tool.

Research article   Open Access

Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes

René J Berckmans, Rienk Nieuwland, Maarten C Kraan, Marianne CL Schaap, Desirée Pots, Tom JM Smeets, Augueste Sturk, Paul P Tak Arthritis Research & Therapy 2005, 7:R536-R544 (1 March 2005)

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Direct interaction of immunoglobulins with synovial fibroblasts: a missing link in the pathogenesis of rheumatoid arthritis?

Thomas Pap Arthritis Res Ther 2005, 7:44-46 (20 December 2004)

Research article   Open Access

Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition

Rebecca K Studer, Rachel Bergman, Tiffany Stubbs, Kimberly Decker Arthritis Res Ther 2004, 6:R56-R64 (7 November 2003)

Viewpoint   Free

New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts

Thomas Pap Arthritis Res Ther 2003, 5:154-155 (10 April 2003)

Research article   Open Access

Osteoclast-independent bone resorption by fibroblast-like cells

Thomas Pap, Anja Claus, Susumu Ohtsu, Klaus M Hummel, Peter Schwartz, Susanne Drynda, Géza Pap, Andreas Machner, Bernhard Stein, Michael George, Renate E Gay, Wolfram Neumann, Steffen Gay, Wilhelm K Aicher Arthritis Res Ther 2003, 5:R163-R173 (26 March 2003)

Research article   Open Access

Functional analysis of an arthritogenic synovial fibroblast

Vassilis Aidinis, David Plows, Sylva Haralambous, Maria Armaka, Petros Papadopoulos, Maria Kanaki, Dirk Koczan, Hans Thiesen, George Kollias Arthritis Res Ther 2003, 5:R140-R157 (14 March 2003)

Research article   Open Access

Expression of interleukin-18 receptor in fibroblast-like synoviocytes

Burkhard Möller, Uta Kessler, Stefan Rehart, Uwe Kalina, Oliver G Ottmann, Joachim Peter Kaltwasser, Dieter Hoelzer, Natasa Kukoc-Zivojnov Arthritis Res 2002, 4:139-144 (14 November 2001)

Commentary   Free

Ex vivo gene transfer in the years to come

Thomas Pap, Renate E Gay, Ulf Müller-Ladner, Steffen Gay Arthritis Res 2002, 4:10-12 (9 October 2001)