Table 2

Association of autoantibodies with shared epitope (SE) alleles

SE/x
 SE/SE
 *0401/*0101
All patients


RF
 1.8
 3.7*
 8.7*
AFA
 2.2*
 5.1*
 9.5*
Anti-Sa
 2.0
 7.1*
 18.9*
Anti-CCP
 2.0
 5.0*
 10.9*
AKA
 1.4
 3.1*
 3.4*




RA patients


RF
 1.8
 2.7
 5.3
AFA
 2.2
 4.9*
 6.5*
Anti-SA
 1.9
 4.0*
 10.6*
Anti-CCP
 2.0
 3.0
 7.2*
AKA
 1.4
 2.9
 3.3

Numbers represent odds ratios for having each autoantibody associated with shared epitope alleles. SE/x, SE/SE, DRB *0401/*0101 were each compared with patients with no shared epitope alleles. *P<0.05 by Chi-square after Bonferroni adjustment for multiple comparison, RF, Rheumatoid factor; AFA, antifilaggrin antibody; CCP, cyclic citrullinated peptide; AKA, antikeratin antibody.

Goldbach-Mansky et al. Arthritis Res 2000 2:236   doi:10.1186/ar93

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