Table 1

Presenting clinical features and prevalence of autoantibodies in rheumatoid factor positive rheumatoid arthritis (RF + RA), RF-negative RA (RF-RA), and nonRA patients


RF + RA
RF - RA
Non RA

(n = 70)
(n = 36)
(n = 132)

Age
47 ± 12
44 ± 14
39 ± 13*
Female
44 (63)
27 (75)
87 (66)
Swollen joint count
13 ± 9
16 ± 10
2 ± 3*
CRP level
1.9 ± 1.9
1.9 ± 2.1
1.6 ± 2.4
Multiple erosions
12 (17)
7 (19)
7 (5)*
RF
70 (100)
0
17 (13)
ANA
25 (36)
10 (28)
30 (23)
ds-DNA
0
0
3(2)
Anti-SSA
5 (7)
2 (6)
7 (5)
Anti-SSB
2 (3)
1 (3)
2 (2)
Anti-RNP
3 (4)
0
3 (2)
Anti-Sm
0
0
2(2)
AFA
32 (46)
3 (8)
9 (7)
Anti-Sa
18 (26)
5(14)
3 (2)
Anti-CCP
38 (54)
5 (14)
12 (9)
AKA
26 (37)
1 (3)
21 (16)
Anti-RA-1
23 (33)
10 (28)
49 (37)
Anti-RA-33
2 (2)
0
1 (1)

All values represent either number of patients (%), or means ± standard deviations. *P<0.01 compared with RA patients; P<0.01 compared with RF - RA and nonRA; P<0.01 compared with nonRA. CRP, C-reactive protein; ANA, antinuclear antibodies; AFA, antifilaggrin antibody; RNP, ribonucleoprotein; CCP, cyclic citrullinated peptide; AKA, antikeratin antibody.

Goldbach-Mansky et al. Arthritis Res 2000 2:236   doi:10.1186/ar93

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