Open Access Highly Accessed Research article

Changes in serum creatinine in patients with active rheumatoid arthritis treated with tofacitinib: results from clinical trials

John D Isaacs1, Andrea Zuckerman2, Sriram Krishnaswami2, Chudy Nduaka2*, Shuping Lan2, Matthew M Hutmacher3, Mary G Boy2, Ken Kowalski3, Sujatha Menon2 and Richard Riese2

Author Affiliations

1 The National Institute for Health Research and Newcastle Biomedical Research Centre based at Newcastle Hospitals Foundation Trust and Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK

2 Pfizer Inc, 558 Eastern Point Road, Groton, CT 06340, USA

3 Ann Arbor Pharmacometrics Group (A2PG), 110 Miller Avenue, Ann Arbor, MI 48104, USA

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Arthritis Research & Therapy 2014, 16:R158  doi:10.1186/ar4673

Published: 25 July 2014

Additional files

Additional file 1:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the Phase 2 A3921019 study.

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Additional file 2:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the LTE A3921024 study.

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Additional file 3:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the Phase 2 A3921025 study.

Format: DOC Size: 269KB Download file

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Additional file 4:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the Phase 3 A3921032 study.

Format: DOC Size: 321KB Download file

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Additional file 5:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the Phase 2 A3921035 study.

Format: DOC Size: 187KB Download file

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Additional file 6:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the Phase 2 A3921039 study.

Format: DOC Size: 71KB Download file

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Additional file 7:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the Phase 2 A3921040 study.

Format: DOC Size: 169KB Download file

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Additional file 8:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the LTE A3921041 study.

Format: DOC Size: 153KB Download file

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Additional file 9:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the Phase 3 A3921044 study.

Format: DOC Size: 424KB Download file

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Additional file 10:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the Phase 3 A3921045 study.

Format: DOC Size: 328KB Download file

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Additional file 11:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the Phase 3 A3921046 study.

Format: DOC Size: 362KB Download file

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Additional file 12:

List of Investigators and Corresponding Ethics Committees or Institutional Review Boards for the Phase 3 A3921064 study.

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Additional file 13: Table S1:

Acute renal failure cases.

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