Table 1

Clinical and laboratory findings in IgG4-related disease, primary Sjögren’s syndrome and healthy controls
Healthy controls IgG4-related disease Primary Sjögren’s syndrome
Number 30 48 38
Gender, male/female, n 7/23 29/19 3/35
Age, years 46.4 ± 10.0 53.17 ± 13.66*** 42.2 ± 9.6
Disease duration, months NA 29.45 ± 41.35* 51.32 ± 47.6
ESR, mm/h NA 49.35 ± 33.80** 30.68 ± 28.35
C-reactive protein, mg/L NA 9.17 ± 3.67** 2.65 ± 1.64
Immunoglobulin (Ig)G, g/L 10.11 ± 1.47 24.58 ± 10.74 22.99 ± 11.48
IgA, g/L 2.28 ± 0.74 1.85 ± 0.76*** 4.17 ± 2.23
IgM, g/L 1.02 ± 0.50 0.82 ± 0.38** 1.24 ± 0.64
IgG1, mg/dL 797.83 ± 106.54 1036.55 ± 670.09** 1485.74 ± 486.36
IgG2, mg/dL 554.6 ± 228.80 592.76 ± 396.55** 372.95 ± 126.70
IgG3, mg/dL 41.68 ± 22.10 78.61 ± 64.05 60.03 ± 41.41
IgG4, mg/dL 57.06 ± 46.06 1929.10 ± 1923.63*** 36.45 ± 37.74
IgG4/total IgG%1 3.90 ± 3.10 39.03 ± 25.84*** 1.86 ± 1.85

Values are shown as mean ± SD unless stated otherwise. 1IgG level is the sum of IgG1, IgG2, IgG3 and IgG4. ***P <0.001; **P <0.01; *P <0.05 (compared with Primary Sjögren’s syndrome). ESR, erythrocyte sedimentation rate; NA, not applicable.

Lin et al.

Lin et al. Arthritis Research & Therapy 2014 16:R118   doi:10.1186/ar4571

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