Prednisone dose correlates with Mer expression on all three monocyte subsets in patients with SLE receiving prednisone; and prednisone treatment increases Mer expression on myeloid dendritic cells. (A) Spearman rank correlation was used to determine the significance of correlation between Mer levels in patients receiving prednisone and dose levels of the prednisone. Values for Spearman r and P value are given for the different correlates in the Table. (B) Mer levels on monocytes were compared between normal healthy controls and SLE patients not treated and treated with prednisone. (C) Mer levels on dendritic cells were compared between normal healthy controls and SLE patients not treated and treated with prednisone. Significance was determined by using the Mann-Whitney rank correlation test. Horizontal bars indicate the median values for the groups. *P < 0.05; **P < 0.001.
Hilliard et al. Arthritis Research & Therapy 2014 16:R76 doi:10.1186/ar4517