Table 3

Hip fracture risk for rs2282679 (GC) and the other SNPs adjusted for independent non-genetic risk factors
Locus SNP HR 95% CI P-value
GC rs2282679 2.52 1.05, 6.05 0.039
DHCR7/NADSYN1 rs3829251 1.00 0.39, 2.56 1.00
rs12785878 0.71 0.22, 2.30 0.56
rs1790349 1.04 0.40, 2.65 0.94
CYP2R1 rs10741657 1.31 0.58, 3.02 0.51

All analyses were adjusted for independent non-genetic factors: Japanese version of the Health Assessment Questionnaire disability score, age, history of total knee replacement, and body mass index [16]. SNP, single nucleotide polymorphism; HR, hazard ratio; GC, group-specific component; DHCR7/NADSYN1, 7-dehydrocholesterol reductase/nicotinamide-adenine dinucleotide synthetase 1; CYP2R1, cytochrome P450, family 2, subfamily R, polypeptide 1.

Yoshida et al.

Yoshida et al. Arthritis Research & Therapy 2014 16:R75   doi:10.1186/ar4516

Open Data