Table 2

Sensitivity (%) and specificity (%) for presymptomatic individuals and rheumatoid arthritis patients. Odds ratio with 95% confidence interval, PPV and NPV calculated for presymptomatic individuals
RA patients (%) Pre RA (%) Specificity (%) ORa 95% CIa P valuea PPV (%) NPV (%)
Survivin 63.9 36.2 88.3 3.43 1.62-7.23 0.0008 43.6 81.6
Flt3L 33.3 6.4 95.5 1.43 0.36-5.77 0.61374 30.0 77.1

CI, confidence interval; Flt3L, Fms-like tyrosine kinase 3 ligand; NPV, negative predictive value calculated for the presymptomatic individuals; OR, odds ratio; PPV, positive predictive value calculated for the presymptomatic individuals; RA, rheumatoid arthritis. aCalculated for presymptomatic individuals compared with controls.

Bokarewa et al.

Bokarewa et al. Arthritis Research & Therapy 2014 16:R45   doi:10.1186/ar4474

Open Data