Table 6

Change in clinical and functional status between baseline and one year by APR levels among biologic-naïve patients
Neither APR elevated APR levels discordant Both APR elevated P value
n = 1,012 n = 487 n = 324
mHAQ 0.00 ± 0.29 -0.06 ± 0.35 -0.14 ± 0.41 <0.0001
CDAI -2.91 ± 10.92 -4.93 ± 12.35 -8.16 ± 13.53 <0.0001
Tender joints -0.91 ± 5.54 -1.69 ± 5.88 -2.82 ± 6.64 <0.0001
Swollen joints -1.28 ± 5.11 -1.85 ± 5.60 -2.81 ± 5.78 <0.0001
Patient global assessment -2.14 ± 26.41 -6.00 ± 27.96 -10.58 ± 30.18 <0.0001
MD global assessment -5.23 ± 16.46 -7.62 ± 19.49 -14.62 ± 22.91 <0.0001

APR, acute phase reactant; mHAQ, modified Health Assessment Questionnaire; CDAI, Clinical Disease Activity Index.

Kay et al.

Kay et al. Arthritis Research & Therapy 2014 16:R40   doi:10.1186/ar4469

Open Data