Additional file 2: Figure S1.
Assessment of global ST inflammation. (A-B) IL-6 and IL-8 gene expression level in STs from RA (n=22) and gout (n=12) patients. Gene expression analysis by qPCR showed that IL-6 and IL-8 expression was similar between RA ST compared to gout ST. Each data point represents a single subject. Results are presented as mean±SEM mRNA expression of IL-6 or IL-8 relative to GAPDH. *p < 0.05, **p < 0.01. (C-D) Immunohistochemical analysis of CD68 and CD163 macrophage markers in RA (n=12), gout (n=11) and HI (n=7) STs. CD68 and CD163 macrophage numbers were increased in RA and gout STs compared to HI STs. No differences were observed between RA and gout STs.
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Ramos et al. Arthritis Research & Therapy 2013 15:R209 doi:10.1186/ar4403