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Open Access Highly Accessed Research article

A complex interaction between Wnt signaling and TNF-α in nucleus pulposus cells

Akihiko Hiyama12*, Katsuya Yokoyama12, Tadashi Nukaga12, Daisuke Sakai12 and Joji Mochida12

Author Affiliations

1 Department of Orthopaedic Surgery, Surgical Science, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan

2 Research Center for Regenerative Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan

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Arthritis Research & Therapy 2013, 15:R189  doi:10.1186/ar4379

Published: 14 November 2013

Additional files

Additional file 1: Figure S1:

The soluble TNF-α protein levels after the stimulation of TNF-α (10 ng/mL, 24 h) by western blotting. The results demonstrate that soluble TNF-α protein was significantly elevated after the stimulation of TNF-α compared to the control cells.

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