Table 2

Comparison of pharmacoepidemiology surveys of gout in ambulatory care settings
Author (year), country Data source Hospital-based clinics included? Specialist visits included? Calendar years of observation Case definition of gout Number of gout cases/visits/episodes Proportion of patients (%)a
Allopurinol Colchicine Any NSAID Systemic steroids
Primatesta (2011), US 1 No Yes 1996 to 2008 ICD codes and gout medication prescription 177,637 36 18 43 20
Reidel (2010), US 1 No Yes 1997 to 1998 ICD codes and gout medication prescription 9,595 66 15 NA NA
Roddy (2010), UK 2 No No 2001 to 2004 Proprietary diagnosis odes 673 23 15 73 0
Annemans (2008), UK 2 No No 2000 to 2005 ICD codes and/or medical record text mentions of gout, and prescription 34,071 89 16 89 26
Annemans (2008), UK 2 No No 2000 to 2005 ICD codes and/or medical record text mentions of gout, and prescription 34,797 93 15 80 14
Harris (1995), UK 3 No No 1993 General practitioner diagnosis 2,865 46 NA NA NA
Mikuls (2005), UK 2 No No 1990 to 1999 Proprietary diagnosis codes 63,105 25 to 30 1 to 3 40 to 66 5%
Cea Soriano (2011), UK 2 No No 2000 to 2007 Proprietary diagnosis codes 24,768 28 14 19 NA
Krishnan (2005), US 4 No Yes 2002 ICD codes and prescriptions 206a 69 4.6 18 6.9
Present study, USc 4 Yes Yes 1993 to 2009 ICD codes alone 100.4 million (1,634b) 35 15 34 10
Present study, USc 4 Yes Yes 1993 to 2009 ICD codes and/or prescriptions 35.9 million (4,781b) 69 17 23 6.8

Settings type 1) Medical and pharmacy insurance claims; 2) General Practice case records with linked pharmacy records; 3) Survey of General practitioners; 4) Nationally representative sample survey of all ambulatory care visits including hospital clinics. aWeighted proportions; bUnweighted number of observations in the dataset; cCumulative, over the study period. NSAID, non-steroidal anti-inflammatory drugs; NA, not available.

Krishnan and Chen

Krishnan and Chen Arthritis Research & Therapy 2013 15:R181   doi:10.1186/ar4370

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