Table 1

Cytokine concentrations in synovial fluid from healthy subjects (n = 5, pooled), and patients with early- (n = 5) and late-stage (n = 5) osteoarthritis
Pro-inflammatory interleukins Sample (n = 5) Mean (pg/mL) SD
IL-6 Healthya 98.35
EOA 717.9 306.50
LOA 1492.01 877.62
IL-1β Healthya 0
EOA 1.45 1.56
LOA 4.64 3.29
IL-8 Healthya 0
EOA 6.58 6.03
LOA 38.63 10.35
IL-17A Healthya 0
EOA 0.02 0.05
LOA 0 0
TNF-alpha Healthya 0
EOA 0.11 0.11
LOA 0.51 0.63
IL-18 Healthya 0.48
EOA 20.38 8.70
LOA 37.29 15.36
Anti-inflammatory interleukins
IL-10 Healthya 1.68
EOA 6.39 1.95
LOA 7.97 3.35

The numeric values depicted for EOA and LOA samples are mean ± SD (concentration range). aCytokine concentrations depicted for healthy synovial fluid samples (n = 5) are values obtained from pooled samples. EOA, early osteoarthritis; LOA, late osteoarthritis.

Wanner et al.

Wanner et al. Arthritis Research & Therapy 2013 15:R180   doi:10.1186/ar4369

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