Figure 4.

Heat maps of early- and late-stage osteoarthritis (OA) sets. Differentially expressed low abundant proteins from early OA (EOA) (A) and late OA (LOA) (B) sets are represented in the form of a heat map. The fold changes of proteins considered from biological replicates were above 1.5/below -1.5. Gene symbols are listed when known. Rows represent the proteins and columns represent the biological replicates in EOA and LOA. Upregulated and downregulated proteins are indicated in shades of green and red, respectively, where the intensity of the color is determined by the distance (in SD) from the mean of the trimmed distribution.

Wanner et al. Arthritis Research & Therapy 2013 15:R180   doi:10.1186/ar4369
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