Additional file 5: Figure S4.
IL-29 shows similar effect on TLR2, 3, 4-mediated IL-6, IL-8 production after two different treatments in MH7A cells. MH7A cells were pretreated with IL-29 (100 ng/ml) for 24 h, and then further stimulated with PGN (2.5 μg/ml), poly I:C (25 μg/ml) or LPS (100 ng/ml). In contrast, MH7A cells were pretreated with PGN (2.5 μg/ml), poly I:C (25 μg/ml) or LPS (100 ng/ml) for 24 h, and then further stimulated with IL-29 (100 ng/ml) for 24 h. The concentration of IL-6 (A) and IL-8 (B) in cell supernatant was examined with ELISA. The data present the mean ± SD for 3 independent experiments. *p < 0.05 versus medium control. **p < 0.01 versus medium control.
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Xu et al. Arthritis Research & Therapy 2013 15:R170 doi:10.1186/ar4357