In vivo, DPTTS inhibits the production of autoantibodies and exerts beneficial effects on local and systemic oxidative stresses in HOCl mice. (a) Serum AOPP levels (micromolar chloramine T equivalents). (b) Levels of anti-DNA topoisomerase-1 Abs measured with ELISA. Values are expressed as mean ± SEM of data gained from all mice in the experimental and control groups. *P < 0.05; ***P < 0.001.
Marut et al. Arthritis Research & Therapy 2013 15:R167 doi:10.1186/ar4351