Decreased expression of epidermal growth factor-like domain 7 (EGFL7) in late-outgrowth peripheral blood endothelial progenitor cell (EPC)-derived endothelial cells from patients with systemic sclerosis (SSc). Western blotting of protein lysates from control (n = 8) and SSc (n = 15) late-outgrowth peripheral blood EPC-derived endothelial cells analyzed using anti-EGFL7 antibodies. Representative immunoblots are shown. The densitometric analysis of the bands normalized to α-tubulin is reported in the histograms. Data are mean ± standard error of the mean of optical density in arbitrary units (a.u.). Student t-test was used for statistical analysis.
Manetti et al. Arthritis Research & Therapy 2013 15:R165 doi:10.1186/ar4349