Table 1

Descriptive baseline characteristics of knees with medial tibia bone marrow lesion (BML) regression, progression, or no change
Variable BML regression (n= 76) No BML or no BML change (n= 156) BML progression (n= 76)
Median (Min, Max) or n (%) Median (Min, Max) or n (%) Median (Min, Max) or n (%)
Age (years) 65 (50, 81) 61 (48, 82) 68 (48, 82)
Body mass index (kg/m2) 29.3 (21.1, 40.9) 29.4 (20.1, 42.0) 29.5 (19.6, 40.7)
Female 40 (52.0%) 85 (54.5%) 38 (50.0%)
Kellgren-Lawrence grade ≥ 2 61 (80.3%) 95 (61.3%) 56 (73.7%)
Baseline BML volume (cm3) 0.55 (0.16, 10.98) 0.10 (0.01, 2.94) 0.15 (0.01, 3.51)
Baseline medial tibia paBMD 1.129 (0.681, 1.890) 1.145 (0.761, 1.743) 1.111 (0.800, 1.664)
Baseline M:L paBMD ratio 1.138 (0.799, 1.549) 1.096 (0.794, 1.779) 1.155 (0.914, 1.385)
Number of knees with baseline BML volume ≥0.50 cm3 43 (56%) 7 (4%) 21 (27%)

Notes: paBMD, periarticular bone mineral density; M:L paBMD ratio, medial-to-lateral paBMD ratio.

Driban et al.

Driban et al. Arthritis Research & Therapy 2013 15:R153   doi:10.1186/ar4336

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