Table 1

Demographic and clinical characteristics of the Spanish patients with RA included in the study
Clinical feature % (n/N)
Patients 502
Main characteristics
Age at the time of disease onset (years, mean ± SD) 50.8 ± 14.5
Follow-up (years, mean ± SD) 9.5 ± 8.1
Percentage of women 77.7
Rheumatoid factor positivea 60.6 (297/490)
Anti-CCP antibodies positive 51.9 (227/437)
Shared epitope positive 62.1 (179/288)
Extra-articular manifestationsb 21 (107/502)
Cardiovascular risk factors
Hypertension 22.7 (110/484)
Diabetes mellitus 6.6 (32/484)
Dyslipidemia 15.1 (73/484)
Obesity 9.7 (47/484)
Smoking habit 27.9 (135/484)
Patients with cardiovascular events 10.7 (54/502)
Ischemic heart disease 4.6 (23/502)
Heart failure 1.9 (10/502)
Cerebrovascular accident 3.8 (19/502)
Peripheral arteriopathy 1.2 (6/502)

aAt least two determinations were required; bextra-articular manifestations of the disease (if RA patients experienced at least one of the following manifestations: nodular disease, Felty’s syndrome, pulmonary fibrosis, rheumatoid vasculitis, or secondary Sjögren’s syndrome) [12]. Anti-CCP antibodies, anti-cyclic citrullinated peptide antibodies; RA, rheumatoid arthritis; SD, standard deviation.

López-Mejías et al.

López-Mejías et al. Arthritis Research & Therapy 2013 15:R152   doi:10.1186/ar4335

Open Data