Table 5

Biochemical parameters associated with antisynthetase syndrome deteriorationa
Biochemical parameters ASS remission/improvement ASS deterioration P
(n= 68) (n= 18)
Overall
 ESR (mm/h) 20 (range: 2 to 108) 32 (range: 8 to 86) 0.09
 C-reactive protein (mg/L) 6 (range: 1 to 104) 13 (range: 3 to 212) 0.172
 Hemoglobin (g/dl) 13.1 (range: 9.8 to 16) 12.9 (range: 10.2 to 15) 1
 Total leukocyte count (giga/L) 6.9 (range: 2.5 to 20.7) 8.3 (range: 3.8 to 25.7) 0.443
 Alanine aminotransferase (IU/L) 57 (range: 11 to 368) 45 (range: 15 to 188) 0.763
 Aspartate aminotransferase (IU/L) 58 (range: 23 to 787) 70 (range: 12 to 376) 0.537
 Creatine kinase (IU/L) 492 (range: 24 to 20,000) 352 (range: 39 to 10,601) 0.861
 Anti-Jo1 antibody titer (U/ml)
  At initial diagnosis of ASS 69 98 0.033
  At last follow-up of ASS 47 135 0.018

aASS: antisynthetase syndrome; ESR: erythrocyte sedimentation rate. Data are medians (ranges) unless otherwise specified. P values were calculated using Fisher’s exact test.

Marie et al.

Marie et al. Arthritis Research & Therapy 2013 15:R149   doi:10.1186/ar4332

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