Table 1

Pharmacokinetics profile of single oral dosing RO9021 in mouse
Dose Cmax (nM) Tmax (hours) T1/2 (hours) AUC (hour*nM)
45 mg/kg 5,763.69 0.50 3.54 35,804.26
5 mg/kg 694.52 1.00 4.34 3,847.84

Cmax, maximum plasma concentration; Tmax, time after administration of a drug when the maximum plasma concentration is reached; T1/2, half-life; AUC, area under the curve.

Liao et al.

Liao et al. Arthritis Research & Therapy 2013 15:R146   doi:10.1186/ar4329

Open Data