Table 4

One-locus analysis of the non–human leukocyte antigen genes included in this studya
SNPs Location BD patients Controls P OR (95% CI)
LOC100129342
 rs11206377 Chr1:39821691
   A 280 (0.48) 279 (0.45)
   G 306 (0.52) 347 (0.55) >0.05
IL23R
 rs17375018 Chr1: 67427735
   A 149 (0.26) 197 (0.32)
   G 431 (0.74) 415 (0.68) 0.01 1.37 (1.06-1.78)
 rs7517847 Chr1:67454257
   G 189 (0.33) 272 (0.43)
   T 391 (0.67) 354 (0.57) 0.0001 1.59 (1.25-2.02)
 rs1343151 Chr1:67491717
   A 192 (0.33) 250 (0.40)
   G 390 (0.67) 374 (0.60) 0.01 1.36 (1.07-1.73)
IL10
 rs3024498 Chr1: 205008152
   C 89 (0.15) 115 (0.18)
   T 495 (0.85) 507 (0.82) >0.05
 rs2222202 Chr1:205012004
   A 200 (0.34) 254 (0.41)
   G 388 (0.66) 366 (0.59) 0.01 1.35 (1.06-1.71)
 rs1800872 Chr1:205013030
   A 172 (0.30) 157 (0.25)
   C 408 (0.70) 463 (0.75) >0.05
CPVL
 rs317711 Chr7:29068833
   C 143 (0.25) 164 (0.27)
   G 429 (0.75) 454 (0.73) >0.05
TDRD7
 rs2061634 Chr9:99145603
   C 453 (0.79) 468 (0.75)
   G 123 (0.21) 154 (0.25) >0.05
UBASH3B
 rs4936742 Chr11:12214629
   C 302 (0.54) 327 (0.53)
   T 258 (0.46) 291 (0.47) >0.05
UBAC2
 rs7999348 Chr13:98730923
   A 407 (0.71) 430 (0.70)
   G 169 (0.29) 182 (0.30) >0.05

aBD, Behçet’s disease; CI, confidence interval; OR, odds ratio; Pc, conditional probability; SNP, single-nucleotide polymorphism. An allelic model was used. Allelic frequencies are the number of each specific allele divided by the total number of alleles (number of individuals × 2) are shown within the parentheses.

Montes-Cano et al.

Montes-Cano et al. Arthritis Research & Therapy 2013 15:R145   doi:10.1186/ar4328

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