Table 2

Demographics of the 214 patients with rheumatoid arthritis and the 1:1 age- and gender-matched control groupa
Characteristics RA Control group P
Hypercholesterolemia (%) 42 28 0.176
Diabetes mellitus (%) 6 13 0.462
Current smokers (%) 30 42 0.089
Women in menopause (%)b 77 61 <0.001
Body mass index (kg/m2) 27.1 ± 5.4 25.6 ± 6.4 0.430
Total cholesterol (mg/dl) 205.6 ± 36.9 199.8 ± 40.6 0.450
Glucose (mg/dl) 93.0 ± 19.0 94.7 ± 31.10 0.419
Creatinine (mg/dl) 0.8 ± 0.2 n/a
eCCL (ml/min) 96.0 ± 33.4 -
C-reactive protein (mg/dl) 4.5 (2.2 to 11.4) 1.0 (0 to 3) <0.001
Use of antihypertensive drugs (%) 44 34c
RA-related drugs (%)
Corticosteroid (%) 70
Methotrexate (%) 58
Leflunomide (%) 17
Cyclosporin (%) 1
Nonsteroidal anti-inflammatory drugs (%) 5
Biologic drugs (%) 35
Hydroxychloroquine (%) 5

aeCCL, estimated creatinine clearance using the Cockcroft-Gault formula; RA, rheumatoid arthritis. The RA patients had a mean age of 58.4 ± 12.3 years, and 82% were females. The study patients were age- and gender-matched 1:1 with a control group from the ATTICA study. Data are presented as means ± SD or medians (interquartile range) and analyzed by paired t-test, χ2 test and Wilcoxon test as appropriate. bData were available for 170 of 176 female RA subjects and 132 of 176 controls. cData are derived from a previously published paper [35].

Protogerou et al.

Protogerou et al. Arthritis Research & Therapy 2013 15:R142   doi:10.1186/ar4324

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