Open Access Research article

ACPA fine-specificity profiles in early rheumatoid arthritis patients do not correlate with clinical features at baseline or with disease progression

Joyce JBC van Beers1, Annemiek Willemze2, Jeroen J Jansen3, Gerard HM Engbers4, Martin Salden5, Jos Raats6, Jan W Drijfhout7, Annette HM van der Helm-van Mil2, Rene EM Toes2 and Ger JM Pruijn1*

Author Affiliations

1 Department of Biomolecular Chemistry, Institute for Molecules and Materials and Nijmegen Center for Molecular Life Sciences, Radboud University Nijmegen, PO Box 9101, NL-6500 HB Nijmegen, The Netherlands

2 Department of Rheumatology, Leiden University Medical Center, PO Box 9600, NL-2300 RC Leiden, The Netherlands

3 Department of Analytical Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, PO Box 9010, NL-6500 GL Nijmegen, The Netherlands

4 Ssens BV, Pantheon 1, NL-7521 PR, Enschede, The Netherlands

5 Euro Diagnostica AB, Toernooiveld 1, NL-6525 ED Nijmegen, The Netherlands

6 ModiQuest BV, Pivot Park RE2142, Molenweg 79, NL-5349 AC Oss, The Netherlands

7 Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, PO Box 9600, NL-2300 RC Leiden, The Netherlands

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Arthritis Research & Therapy 2013, 15:R140  doi:10.1186/ar4322

Published: 1 October 2013

Additional files

Additional file 1:

Supplementary Materials and Methods; Supplementary Tables S1 and S2; Supplementary Figures S1–S3.

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