Table 4

Individual target tophus response categories at patient’s final visit in the randomized trialsa
Categories Pegloticase Pegloticase Placebo
biweekly monthly
(n = 62) (n = 64) (n = 29)
Total number of tophib 229 201 117
Response category, n (%)
  CR 57 (25) 30 (15) 2 (2)
  PR or MR 49 (21) 33 (16) 12 (10)
  SD 111 (49) 121 (60) 89 (76)
  PD 1 (0.4) 1 (0.5) 3 (3)
  Unable to evaluate 11 (5) 16 (8) 11 (9)

aCR, complete response; MR, marked response; PD: progressive disease; PR, partial response; SD: stable disease. bTotal tophi includes both measurable and unmeasurable tophi.

Baraf et al.

Baraf et al. Arthritis Research & Therapy 2013 15:R137   doi:10.1186/ar4318

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