Consolidated Standards of Reporting Trials Statement (CONSORT) diagram for the pooled tophus-evaluable population. This population flowchart shows the disposition of all patients with baseline tophi pooled from the two randomized, placebo-controlled trials of pegloticase known as GOUT 1 and GOUT 2. OLE, open-label extension; RCT, randomized controlled trial.
Baraf et al. Arthritis Research & Therapy 2013 15:R137 doi:10.1186/ar4318