Representative interleukin 17 and interleukin 22 expression patterns in synovial tissue from osteoarthritis, rheumatoid arthritis and psoriatic arthritis patients. (A) Positive cells show red staining; original magnification, ×200. (B) and (C) Semiquantitative (SQ) analysis shows grading of the percentage of cells present in entire tissue: 0 = no staining, 1 = <10%, 2 = 10% to 25%, 3 = 25% to 50% and 4 = >50% for both (B) interleukin 17-positive (IL-17+) and (C) IL-22+ in tissue samples from patients with osteoarthritis (OA), rheumatoid arthritis (RA) and psoriatic arthritis (PsA). * p<0.05, **p<0.01, ***p<0.001.
Benham et al. Arthritis Research & Therapy 2013 15:R136 doi:10.1186/ar4317