Secretion of interleukin 17 and interleukin 22 by peripheral blood mononuclear cells from psoriatic arthritis and psoriasis patients and from healthy controls. The concentrations (Conc) of interleukin 17 (IL-17) (A) and IL-22 (B) in culture supernatants of peripheral blood mononuclear cells from patients with psoriasis (Ps) and patients with psoriatic arthritis (PsA) and from healthy controls four days after stimulation with anti-CD3/CD28. Correlations between percentages of IL-17+ and IL-22+CD4+ T cells and the concentrations of IL-17 (C) and IL-22 (D) in culture supernatants. * p<0.05, **p<0.01, ***p<0.001.
Benham et al. Arthritis Research & Therapy 2013 15:R136 doi:10.1186/ar4317