Table 4

Independent relations of high molecular weight adiponectin concentrations* with cardiometabolic risk and surrogate markers of enhanced early atherogenesis in African black and white patients with rheumatoid arthritis
Patients
Interaction All (n = 210) Black (n = 119) White (n = 91)
Characteristic Partial R P Partial R P Partial R P Partial R P
Metabolic risk factor
 Systolic blood pressure 0.122 0.09 0.217 0.002 0.304 0.001 0.123 0.1
 Diastolic blood pressure 0.022 0.7 0.155 0.03 0.257 0.01 0.143 0.2
 Mean blood pressure 0.107 0.1 0.216 0.002 0.298 0.002 0.143 0.2
 Total cholesterol -0.149 0.04 -0.002 1.0 -0.095 0.3 0.074 0.5
 HDL cholesterol* 0.214 0.003 0.214 0.003 0.292 0.003 0.180 0.1
 Total-HDL cholesterol ratio -0.190 0.009 -0.196 0.006 -0.302 0.002 -0.112 0.3
 LDL cholesterol -0.119 0.1 -0.036 0.6 -0.121 0.2 0.018 0.8
 Non-HDL cholesterol -0.190 0.009 -0.094 0.1 -0.221 0.03 -0.002 1.0
 Triglycerides* -0.212 0.009 -0.137 0.05 -0.269 0.006 -0.003 0.9
 Triglycerides-HDL cholesterol ratio* -0.211 0.003 -0.202 0.004 -0.329 0.0008 0.094 0.4
 Glucose* -0.215 0.003 -0.155 0.03 -0.246 0.01 -0.143 0.2
 Number of metabolic risk factors -0.193 0.007 -0.155 0.03 -0.210 0.03 -0.148 0.2
Early atherogenesis
 Selectin -0.044 0.5 -0.013 0.9 -0.051 0.6 -0.019 0.8
 VCAM-1* -0.079 0.2 0.128 0.08 -0.007 0.9 0.240 0.03
 ICAM-1* -0.129 0.08 0.103 0.1 -0.007 0.9 0.286 0.009
 MCP-1* -0.054 0.4 0.021 0.8 -0.011 0.9 0.153 0.1
 Endothelial activation score -0.123 0.07 0.098 0.1 -0.058 0.5 0.252 0.02

Relationships were determined in demographic characteristic, log glomerular filtration, cardiovascular drug use and waist circumference adjusted models. Significant associations are shown in bold. *Log transformed. HDL, High density lipoprotein; ICAM, Intercellular adhesion molecule; LDL, low density lipoprotein; MCP, Monocyte chemoattractant protein; VCAM, Vascular cell adhesion molecule.

Dessein et al.

Dessein et al. Arthritis Research & Therapy 2013 15:R128   doi:10.1186/ar4308

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