Table 3

Independent relations of total adiponectin concentrations* with cardiometabolic risk and surrogate markers of enhanced early atherogenesis in African black and white patients with rheumatoid arthritis
Patients
Interaction All (n = 210) Black (n = 119) White (n = 91)
Characteristic Partial R P Partial R P Partial R P Partial R P
Metabolic risk factor
 Systolic blood pressure 0.039 0.6 0.232 0.001 0.304 0.001 0.157 0.1
 Diastolic blood pressure -0.032 0.7 0.203 0.004 0.248 0.01 0.200 0.07
 Mean blood pressure 0.026 0.7 0.241 0.008 0.298 0.002 0.181 0.1
 Total cholesterol -0.139 0.06 -0.164 0.02 -0.138 0.1 -0.213 0.06
 HDL cholesterol* 0.201 0.005 0.126 0.08 0.360 0.002 -0.170 0.1
 Total-HDL cholesterol ratio -0.270 0.0002 -0.231 0.001 -0.390 <0.0001 -0.027 0.9
 LDL cholesterol -0.131 0.07 -0.158 0.03 -0.178 0.08 -0.142 0.2
 Non-HDL cholesterol -0.244 0.0007 -0.209 0.004 -0.292 0.003 -0.132 0.2
 Triglycerides* -0.204 0.005 -0.231 0.003 -0.299 0.002 -0.060 0.5
 Triglycerides-HDL cholesterol ratio* -0.254 0.0004 -0.221 0.002 -0.379 <0.0001 0.045 0.7
 Glucose* -0.104 0.1 -0.126 0.08 -0.109 0.3 -0.304 0.006
 Number of metabolic risk factors -0.244 0.0007 -0.120 0.1 -0.238 0.01 0.047 0.6
Early atherogenesis
 Selectin -0.068 0.3 -0.040 0.6 -0.062 0.5 -0.029 0.7
 VCAM-1* -0.165 0.02 0.122 0.09 -0.020 0.8 0.262 0.01
 ICAM-1* -0.109 0.1 0.012 0.9 -0.083 0.4 0.147 0.1
 MCP-1* -0.122 0.09 0.100 0.2 -0.001 1.0 0.297 0.006
 Endothelial activation score -0.203 0.005 0.080 0.3 -0.071 0.4 0.262 0.01

Relationships were determined in demographic characteristic, log glomerular filtration, cardiovascular drug use and waist circumference adjusted models. Significant associations are shown in bold. *Log transformed. HDL, High density lipoprotein; ICAM, Intercellular adhesion molecule; LDL, Low density lipoprotein; MCP, Monocyte chemoattractant protein; VCAM, Vascular cell adhesion molecule.

Dessein et al.

Dessein et al. Arthritis Research & Therapy 2013 15:R128   doi:10.1186/ar4308

Open Data