Table 3

Mean fluorescence ratios (standardized for overall perfusion of the hand) for joints with compared with those without evidence of synovitis determined by clinical examination or established imaging techniques #
Ratio FOI phase 1 (1 – 120 seconds) Ratio FOI phase 2 (121 – 240 seconds) Ratio FOI phase 3 (241 – 360 seconds)
Synovitis n Mean ± SD P Mean ± SD P Mean ± SD P
TJ yes 44 1.02 ± 0.45 ns 1.31 ± 0.48 * 1.33 ± 0.48 *
TJ no 46 0.93 ± 0.33 1.10 ± 0.23 1.13 ± 0.24
SJ yes 26 1.13 ± 0.50 * 1.43 ± 0.54 ** 1.45 ± 0.54 **
SJ no 64 0.91 ± 0.33 1.11 ± 0.26 1.14 ± 0.26
GSUS yes 39 1.06 ± 0.47 ns 1.33 ± 0.48 * 1.37 ± 0.48 **
GSUS no 51 0.91 ± 0.32 1.10 ± 0.26 1.12 ± 0.26
CDUS yes 23 1.22 ± 0.46 ** 1.52 ± 0.52 ** 1.53 ± 0.53 **
CDUS no 67 0.89 ± 0.33 1.09 ± 0.26 1.12 ± 0.26
MRI yes 39§ 1.11 ± 0.46 ** 1.38 ± 0.47 *** 1.41 ± 0.46 ***
MRI no 40§ 0.86 ± 0.33 1.06 ± 0.26 1.08 ± 0.26
All 90 0.97 ± 0.39 1.20 ± 0.39 1.22 ± 0.39

# Fluorescence ratios were derived by dividing the readout of each joint by the readout of the control area of the eponychium of the index finger; § 11 joints could not be evaluated with MRI; *P<0.05; **P<0.01; ***P<0.001.

CDUS, color Doppler ultrasonography; FOI, fluorescence optical imaging; GSUS, grey-scale ultrasonography; MRI, magnetic resonance imaging; ns, comparison was not significant (P≥0.05 with student’s t-test); SD, standard deviation; SJ, swollen joint by clinical examination; TJ, tender joint by clinical examination.

Schäfer et al.

Schäfer et al. Arthritis Research & Therapy 2013 15:R124   doi:10.1186/ar4304

Open Data