Table 2

Mean fluorescence readout for joints with compared to those without evidence of synovitis determined by clinical examination or established imaging techniques #
FOI phase 1 (1 – 120 seconds) FOI phase 2 (121 – 240 seconds) FOI phase 3 (241 – 360 seconds)
Synovitis n mean ± SD P mean ± SD P mean ± SD P
TJ yes 44 19.1 ± 11.0 ns 19.6 ± 9.0 ns 12.6 ± 5.7 ns
TJ no 46 19.2 ± 7.8 19.6 ± 9.4 13.0 ± 7.8
SJ yes 26 22.7 ± 12.6 ns 22.3 ± 9.8 ns 14.1 ± 6.2 ns
SJ no 64 17.7 ± 7.5 18.5 ± 8.7 12.3 ± 7.0
GSUS yes 39 21.0 ± 11.4 ns 23.5 ± 10.4 ** 15.8 ± 7.9 **
GSUS no 51 17.7 ± 7.5 16.6 ± 6.8 10.5 ± 4.8
CDUS yes 23 24.1 ± 12.3 * 23.8 ± 9.3 * 15.0 ± 5.9 ns
CDUS no 67 17.5 ± 7.7 18.2 ± 8.7 12.0 ± 7.0
MRI yes 39§ 20.9 ± 10.1 ns 22.3 ± 9.5 * 14.8 ± 7.3 *
MRI no 40§ 17.8 ± 9.6 17.2 ± 9.2 10.9 ± 6.5
All 90 19.1 ± 9.4 19.6 ± 9.2 12.8 ± 6.8

# Fluorescence readout results are displayed for better readability divided by 103; § 11 joints could not be evaluated with MRI; *P<0.05; **P<0.01.

CDUS color Doppler ultrasonography, FOI fluorescence optical imaging, GSUS grey-scale ultrasonography, MRI magnetic resonance imaging; ns, comparison was not significant (P≥0.05 with student’s t-test), SD standard deviation, SJ swollen joint by clinical examination, TJ tender joint by clinical examination.

Schäfer et al.

Schäfer et al. Arthritis Research & Therapy 2013 15:R124   doi:10.1186/ar4304

Open Data