Myeloperoxidase (MPO) activation in the lungs is abrogated by propylthiouracil administration. MPO activity was defined as the quantity of enzyme degrading 1 μM hydrogen peroxide/minute at 37°C and was expressed in units per 100 mg of tissue. *P < 0.001 versus Sham; #P < 0.001 versus HOCl. HOCl group (n = 10), HOCl + PTU group (n = 10), Sham (n = 5).
Bagnato et al. Arthritis Research & Therapy 2013 15:R120 doi:10.1186/ar4300