Figure 4.

Immunostaining for α-SMA (arrows are illustrative for myofibroblasts nuclei) in pulmonary samples. Representative tissue sample from: (A) Sham animal; (B) HOCl mice; (C) HOCl + PTU animal (Original magnification, ×40). The arrows show strong diffuse staining of myofibroblasts nuclei (dark brown staining); (D) Number of myofibroblasts from the three experimental groups (HOCl + PTU group, n = 10; HOCl group, n = 10; Sham, n = 5). The increase of myofibroblast population in the skin of HOCl mice is prevented by propylthiouracil administration. Values are expressed as the mean and SD. *p < 0.001 versus Sham; #p < 0.001 versus HOCl.

Bagnato et al. Arthritis Research & Therapy 2013 15:R120   doi:10.1186/ar4300
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