Table 4

Effect of plaque on functional assessments of endothelial function.

Evidence of left plaque

Evidence of right plaque

No

Yes

P value

No

Yes

P value


Microvascular endothelial function

ACh (%)

242.5 (128.3-454.5)

179.5 (95.5-274.5)

0.092

262.0 (130.7-462.0)

152.0 (102.3-214.3)

0.032*

SNP (%)

144.0 (75.5-243.5)

120.0 (23.0-205.0)

0.221

140.5 (74.0-244.0)

143.0 (58.8-223.8)

0.700

Macrovascular endothelial function

FMD (%)

10.8 ± 7.2

10.5 ± 9.1

0.866

10.9 ± 7.4

9.7 ± 6.8

0.537

GTN (%)

22.7 ± 9.2

17.2 ± 9.7

0.061

23.1 ± 9.1

15.5 ± 8.3

0.002**


Microvascular endothelial function data displayed as: median (quartiles), with P values from Mann-Whitney tests. Macrovascular endothelial function data displayed as mean ± standard deviation, with P values from t tests. *Significant at P < 0.05; **significant after Bonferroni adjustment for eight comparisons at P < 0.006. ACh, acetylcholine; SNP, sodium nitroprusside; FMD, flow-mediated dilatation; GTN, glyceryl-trinitrate mediated dilatation.

Sandoo et al. Arthritis Research & Therapy 2013 15:R107   doi:10.1186/ar4287

Open Data