Table 3

Association between sociodemographic, general health and disease-specific variables to health-related quality of lifea

SF-36 PCS

SF-36 MCS


Crude MD (95% CI)

Adjusted MD (95% CI)b

Adjusted MD (95% CI)c

Crude MD (95% CI)

Adjusted MD (95% CI)b

Adjusted MD (95% CI)c


Sociodemographic variables

Gender (female vs. male)

-7.37 (-10.67, -4.08)

-3.45 (-6.44, -0.45)

Age (5 years)

-1.04 (-1.45, -0.64)

-0.15 (-0.52, 0.23)

Education

No or primary

Reference

Reference

Secondary

1.44 (-0.96, 3.84)

-0.26 (-2.69, 2.18)

0.52 (-1.68, 2.73)

0.42 (-1.90, 2.73)

Upper secondary

5.71 (3.32, 8.10)

3.95 (1.48, 6.41)

2.15 (-0.06, 4.35)

2.11 (-0.24, 4.45)

Tertiary

5.40 (1.84, 8.97)

3.84 (0.26, 7.41)

2.30 (-0.98, 5.58)

2.46 (-0.94, 5.86)

Employment

Employed

Reference

Reference

Unemployed

-6.05 (-10.16, -1.94)

-3.10 (-7.31, -1.11)

-2.74 (-6.50, 1.03)

-1.83 (-5.77, 2.12)

Retired

-4.59 (-6.69, -2.49)

-1.99 (-4.85, 0.88)

-0.21 (-2.13, 1.71)

0.34 (-2.34, 3.01)

Unknown

-

-

-

-

General health variables

Comorbidity index

-1.12 (-1.34, -0.90)

-0.98 (-1.22, -0.74)

-0.58 (-0.80, -0.37)

-0.62 (-0.85, -0.39)

Body mass index

Normal

Reference

Reference

Overweight

-2.4 7 (-4.97, 0.04)

-2.98 (-5.38, -0.58)

-1.06 (-3.32, 1.20)

-1.45 (-3.71, 0.81)

Obese

-4.87 (-7.73, -2.01)

-5.79 (-8.51, -3.06)

-2.35 (-4.92, 0.22)

-2.72 (-5.29, -0.16)

Current smokers

0.04 (-2.60, 2.67)

-0.90 (-3.45, 1.64)

0.47 (-1.9, 2.84)

0.3 (-2.08, 2.68)

High alcohol consumers

0.57 (-1.47, 2.60)

-0.58 (-2.56, 1.39)

-0.94 (-2.77, 0.88)

-1.33 (-3.17, 0.52)

Gout-related variables

Disease duration (>5 years)

-2.54 (-4.49, -0.58)

-2.37 (-4.25, -0.49)

-1.70 (-3.45, 0.05)

-2.54 (-4.29, -0.79)

-2.61 (-4.35, -0.86)

-2.08 (-3.79, -0.37)

Joint involvement

Monoarticular

Reference

Reference

Oligoarticular (2 to 4 joints)

-3.13 (-5.53, -0.73)

-3.35 (-5.64, -1.06)

-2.22 (-4.38, -0.07)

0.40 (-1.78, 2.57)

0.27 (-1.90, 2.44)

0.96 (-1.18, 3.10)

Polyarticular (>4 joints)

-5.66 (-8.69, -2.62)

-5.92 (-8.82, -3.01)

-3.79 (-6.55, -1.04)

-1.05 (-3.80, 1.70)

-1.25 (-4.00, 1.50)

0.42(-2.30, 3.16)

Number of attacks last year

-0.70 (-0.94, -0.47)

-0.71 (-0.93, -0.49)

-0.56 (-0.77, -0.36)

-0.45 (-0.66, -0.24)

-0.44 (-0.65, -0.23)

-0.34 (-0.55, -0.13)

Attacks last month

-8.18 (-10.15, -6.20)

-8.62 (-10.49, -6.76)

-8.13 (-9.88, -6.38)

-3.22 (-5.09, -1.35)

-3.33 (-5.20, -1.47)

-2.72 (-4.58, -0.86)

Presence of tophi

-4.72 (-7.15, -2.30)

-4.16 (-6.50, -1.83)

-3.20 (-5.41, -0.99)

0.56 (-1.62, 2.75)

0.71 (-1.47, 2.89)

1.26 (-0.88, 3.40)

Number of swollen joints

-0.91 (-1.17, -0.65)

-0.78 (-1.04, -0.53)

-0.54 (-0.79, -0.29)

-0.40 (-0.64, -0.16)

-0.37 (-0.62, -0.13)

-0.20 (-0.45, 0.04)

Number of tender joints

-0.64 (-0.79, -0.49)

-0.58 (-0.73, -0.42)

-0.39 (-0.55, -0.24)

-0.38 (-0.52, -0.24)

-0.36 (-0.51, -0.21)

-0.24 (-0.39, -0.09)

Serum uric acid

<5 mg/dl

Reference

Reference

5 to 6 mg/dl

-0.09 (-3.14, 2.96)

-0.15 (-3.06, 2.76)

-0.60 (-3.24, 2.02)

-0.2 (-2.97, 2.57)

-0.23 (-2.99, 2.52)

-0.66 (3.19, 1.86)

6 to 7 mg/dl

-0.12 (-3.09, 2.86)

-0.60 (-3.46, 2.26)

0.48 (-2.32, 3.29)

-1.68 (-4.38, 1.03)

-1.71 (-4.42, 0.99)

-0.75 (-3.55, 2.04)

>7 mg/dl

-1.78 (-4.56, 0.99)

-2.95 (-5.63, -0.28)

-2.06 (-4.51, 0.38)

-1.45 (-3.98, 1.07)

-1.78 (-4.31, 0.76)

-1.00 (-3.39, 1.38)

Urate-lowering treatment

0.41 (-2.05, 2.87)

0.37 (-2.01, 2.75)

0.49 (-1.71, 2.69)

0.27 (-1.94, 2.47)

0.06 (-2.16, 2.27)

0.03 (-2.12, 2.19)

Current NSAIDs or colchicine

-7.03 (-8.95, -5.11)

-6.67 (-8.52, -4.82)

-5.47 (-7.38, -3.56)

-2.79 (-4.57, -1.00)

-2.53 (-4.32, -0.75)

-2.13 (-4.04, -0.23)

Previous corticosteroids

-5.10 (-7.26, -2.95)

-4-67 (-6.75, -2.59)

-3.51 (-5.46, -1.26

-4.15 (-6.06, -2.23)

-3.90 (-5.83, -1.98)

-3.39 (-5.30, -1.48)


aAssessed by the Short Form-36 (SF-36) questionnaire, physical and mental summary score. CI, confidence interval; MCS, Mental Component Summary; MD, mean difference; PCS, Physical Component Summary. aAdjusted for age and gender. bAdjusted for age, gender, comorbidities, body mass index, smoking, high alcohol consumption, education and employment (on 10 imputed datasets).

Scirè et al. Arthritis Research & Therapy 2013 15:R101   doi:10.1186/ar4281

Open Data