Neutrophil extracellular traps in neutrophils from a rheumatoid arthritis patient, following in vitro stimulation. Neutrophil extracellular traps (NETs) visualized in neutrophils isolated from a patient with rheumatoid arthritis, following stimulation with recombinant IL-17A in vitro. Prominent NET formation is displayed, with DNA visualized in blue (4′,6-diamidino-2-phenylindole) and neutrophil elastase in red. Original magnification 40×. Microphotograph obtained by Dr Carmelo Carmona-Rivera.
Kaplan Arthritis Research & Therapy 2013 15:219 doi:10.1186/ar4325