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Open Access Highly Accessed Research article

Transcriptomic signatures in cartilage ageing

Mandy Jayne Peffers1*, Xuan Liu2 and Peter David Clegg1

Author Affiliations

1 Comparative Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool, Leahurst, Chester High Road, Neston, Wirral CH64 7TE, UK

2 Centre for Genomic Research, Institute of Integrative Biology, Biosciences Building, Crown Street, University of Liverpool, Liverpool L69 7ZB, UK

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Arthritis Research & Therapy 2013, 15:R98  doi:10.1186/ar4278

Published: 23 August 2013

Additional files

Additional file 1:

Table S1 presenting a complete list of significantly expressed genes and DAVID analysis of the expression patterns. The first two spreadsheets contain the DAVID results for annotation cluster analysis. The next two sheets contain the KEGG results from DAVID.

Format: XLSX Size: 191KB Download file

Open Data

Additional file 2:

Table S2 presenting IPA generated networks of differentially expressed genes. Network eligible molecules were overlaid onto molecular networks, and networks were then generated based on connectivity. All identified networks and their respective molecules are tabulated.

Format: CSV Size: 8KB Download file

Open Data

Additional file 3:

Table S3 presenting IPA canonical pathways. Significant IPA canonical pathways and the associated molecules relating to these pathways.

Format: XLSX Size: 21KB Download file

Open Data