Table 5

Relationships of disease activity and severity with systemic inflammation in non- or mildly active RA.

C-reactive proteina

Interleukin-6a



Disease activity variable

Age and sex adjusted model

Multivariable adjusted modelb

Age and sex adjusted model

Multivariable

adjusted modelb


Partial R

P

Partial R

P

Partial R

P

Partial R

P

Swollen jointsa

0.082

0.6

0.063

0.7

-0.189

0.2

-0.147

0.3

Tender jointsa

-0.067

0.6

-0.100

0.5

-0.173

0.2

-0.168

0.3

Doctor disease activitya

0.044

0.8

0.017

0.9

-0.126

0.4

-0.027

0.9

Patient disease activity

-0.148

0.3

-0.139

0.3

0.070

0.6

0.011

0.9

CDAIa

-0.034

0.8

-0.060

0.7

-0.143

0.3

-0.116

0.4

Deformed jointsa

0.071

0.6

0.119

0.4

-0.081

0.6

0.013

0.9


Fifty-four patients had no or mild disease activity (CDAI = 0 to 10). aNon-normally distributed variables that were logarithmically transformed; badditionally adjusted for potential confounders of body mass index, waist:height ratio and angiotensin converting enzyme inhibitors (see Table 3). CDAI, Clinical Disease Activity Index.

Dessein et al. Arthritis Research & Therapy 2013 15:R96   doi:10.1186/ar4276

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