Table 4

Relationships of disease activity and severity with systemic inflammation in all 115 African RA patients

C-reactive proteina

Interleukin-6a



Disease activity variable

Age and sex adjusted model

Multivariable adjusted modelb

Age and sex adjusted model

Multivariable

adjusted modelb


Partial R

P

Partial R

P

Partial R

P

Partial R

P

Swollen jointsa

0.081

0.4

0.102

0.3

-0.136

0.2

-0.101

0.3

Tender jointsa

0.005

1.0

0.009

0.9

-0.029

0.8

-0.012

0.9

Doctor disease activitya

0.061

0.5

0.057

0.6

0.077

0.4

0.126

0.2

Patient disease activity

-0.053

0.6

0.082

0.4

0.101

0.3

0.090

0.4

CDAIa

0.065

0.5

0.049

0.6

0.083

0.4

0.031

0.8

CDAI >2.7

0.069

0.5

0.088

0.4

0.129

0.2

0.163

0.1

Deformed jointsa

0.040

0.7

0.103

0.3

-0.027

0.8

-0.016

0.9


aNon-normally distributed variables that were logarithmically transformed; badditionally adjusted for potential confounders of body mass index, waist:height ratio and angiotensin converting enzyme inhibitors (see Table 3). CDAI, Clinical Disease Activity Index.

Dessein et al. Arthritis Research & Therapy 2013 15:R96   doi:10.1186/ar4276

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