Table 3

Associations of potential determinants of systemic inflammation with CRP and interleukin-6 concentrations in all participants

C-reactive proteina

Interleukin-6a



Potential determinant

Age and sex adjusted model

Multivariable adjusted model

Age and sex adjusted model

Multivariable adjusted model


Partial R

P

Partial R

P

Partial R

P

Partial R

P

Body mass index

0.240

0.0003

-0.005

0.9

0.227

0.0002

0.148

0.02

Waist circumference

0.318

<0.0001

0.173

0.005

Waist/height

0.302

<0.0001

0.188

0.005

0.182

0.004

-0.001

1.0

Waist/hipa

0.163

0.01

0.054

0.39

Number of cigarettes/daya

0.017

0.8

0.034

0.6

0.128

0.04

0.130

0.04

Alcohol use

0.065

0.3

0.048

0.5

0.162

0.008

0.098

0.1

ACE inhibitor use

0.051

0.4

0.056

0.4

-0.144

0.019

-0.127

0.045

Model

0.350

0.331


Significant associations are shown in bold. aNon-normally distributed variables that were logarithmically transformed. Except for alcohol use (only in participants without rheumatoid arthritis), none of the relationships differed in black Africans with versus those without rheumatoid arthritis (interaction P = 0.1 to 0.9). CRP, C-reactive protein.

Dessein et al. Arthritis Research & Therapy 2013 15:R96   doi:10.1186/ar4276

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