Table 3

HLA-DRB1 alleles classified according to du Montcel et al.

du Montcel classification

Amino acid sequence positions 70 to 74

HLA-DRB1

Patient group % (n)

Controls % (n)

SE

OR

95% CI

P-value


S2

QKRAA

*04:01

4.1 (3)

4.2 (2)

positive

2.6

0.8 to 8.3

0.124

DKRAA

*13:03

S3P

QRRAA

*01:01/02

14.9 (11)

4.2 (2)

RRRAA

*10

S1

DERAA

*11:02, *13:01/02

81.0 (60)

91.6 (44)

negative

QARAA

*15

S3D

DRRAA

*11:01, *12, *16

X

nonXXRAA

*03,*07,*08,*09,*14


[14], in RA patients and controls (homozygous alleles are counted double)

OR, odds ratio; RA, rheumatoid arthritis; SE, shared epitope; A, alanin; D, aspartic acid aspartique; E, glutamic acid; K, leucin; Q, glutamin; R, arginin

Malemba et al. Arthritis Research & Therapy 2013 15:R89   doi:10.1186/ar4269

Open Data