Table 6

Ischemic arterial events and surrogate measures of atherosclerosis in ACA+ patients versus ACA-patients and controls.

Occurrence of events and atherosclerosis

ACA+ vs. ACA-

ACA+ vs. controls


ACA+

(n = 34)

ACA-

(n = 77)

Controls

(n = 105)

Odds ratio**

(95% CI)

P value**

Odds ratio*

(95% CI)

P value*


Any arterial event % (n)

32 (11)

11 (9)

7 (7)

5.1 (1.57-18.6)

0.01

8.5 (2.6-31.7)

0.0003

IHD % (n)

18 (6)

9 (7)

4 (4)

2.6 (0.7-10.0)

0.2

4.8 (1.2-20.7)

0.02

ICVD % (n)

6 (2)

3 (2)

3 (3)

4.0 (0.4-49.0)

0.2

2.0 (0.2-13.9)

0.6

IPVD % (n)

18 (6)

4 (3)

1 (1)

9.1 (1.6-79.1)

0.01

70.1 (6.5-2524)

<0.0001

Plaque % (n)

65 (22)

39 (30)

41 (43)

3.1(1.2-8.5)

0.02

2.8 (1.1-7.6)

0.04

β-coefficient

β-coefficient

IMT mm

0.69 ± 0.13

0.68 ± 0.13

0.68 ± 0.13

0.03

0.7

0.01

0.6

ABI

1.1(1.03-1.2)

1.1 (1.17-1.2)

1.1 (1.07-1.2)

-0.12

0.08

-0.14

0.07


Distributions are given as %, median (interquartile range) or mean ± standard deviation. **adjusted for age, sex and disease duration; *adjusted for age and sex. ACA, anticentromere antibodies; +, positivity; -, negativity; CI, confidence interval; IHD, ischemic heart disease; ICVD, ischemic cerebrovascular disease; IPVD, ischemic peripheral vascular disease; IMT, intima-media thickness; ABI, ankle-brachial index.

Nordin et al. Arthritis Research & Therapy 2013 15:R87   doi:10.1186/ar4267

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