Table 2

ACR classification criteria for patients with normal and decreased ability to degrade NETs

ACR classification criteria

Normal

(n = 41)

number (%)

Decreased at least once (n = 28)

number (%)

P-value (Pearson)


Malar rash

27 (66%)

19 (68%)

0.86

Discoid rash

12 (30%)

6 (21%)

0.47

Photosensitivity

30 (73%)

12 (43%)

0.01*

Oral ulcer

8 (20%)

8 (29%)

0.38

Arthritis

32 (78%)

23 (82%)

0.68

Serositis

18 (44%)

17 (61%)

0.17

Nephritis

19 (46%)

16 (57%)

0.38

Neurological disorder

2 (5%)

1 (4%)

0.79

Hematological disorder

21 (51%)

17 (61%)

0.44

Immunological disorder

27 (66%)

26 (93%)

0.009*

Anti-dsDNA

22 (54%)

23 (82%)

0.01*

Anti-Sm

4 (10%)

3 (11%)

0.90

False positive Wasserman

5 (12%)

1 (4%)

0.21

Anti-nuclear antibodies

41 (100%)

28 (100%)

-


American College of Rheumatology (ACR) classification criteria reflect the clinical history of systemic lupus erythematosus (SLE) and are compared for patients who always displayed normal ability to degrade neutrophil extracellular traps (NETs) compared to patients who at least once displayed a decreased ability to degrade NETs. Asterisks indicate significant differences with the increased proportion highlighted by bold numbers.

Leffler et al. Arthritis Research & Therapy 2013 15:R84   doi:10.1186/ar4264

Open Data