Table 2

Frequency of the minor allele of P2RX7 A1405 G allele in pSS patients and controls

Cohort

Group

Number

A1405G MAFa

Odds ratio (95% CI)

P-value


Cohort 1

Controls

136

0.15

1

All pSS

114

0.20

1.46 (0.91, 2.34)

0.12

Seronegative pSS

19

0.07

0.44 (0.13,1.52)

0.22

Seropositive pSS

95

0.23

1.78 (1.09, 2.92)

0.02

Cohort 2

Controls

534

0.15

1

All pSS

281

0.17

1.07 (0.79, 1.45)b

0.64

Seronegative pSS

82

0.21

1.35 (0.87, 2.10) b

0.18

Seropositive pSS

199

0.16

0.96 (0.68, 1.36) b

0.83


aMAF, minor allele frequency; bprincipal components adjusted analysis; pSS, primary Sjögren's syndrome.

Lester et al. Arthritis Research & Therapy 2013 15:R71   doi:10.1186/ar4248

Open Data