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Open Access Highly Accessed Research article

Genomic characterization of remission in juvenile idiopathic arthritis

Kaiyu Jiang13, Mark Barton Frank2, Yanmin Chen13, Jeanette Osban2 and James N Jarvis13*

Author Affiliations

1 Department of Pediatrics, Pediatric Rheumatology Research, University of Oklahoma Health Sciences Center, Basic Sciences Education Building 235A, Oklahoma City, OK 73104, USA

2 Microarray Research Facility, Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, 840 NE 13th Street, Oklahoma City, OK 73104, USA

3 Department of Pediatrics, Rheumatology Research, SUNY Buffalo Clinical and Translational Research Center, 875 Ellicott Street, Buffalo, NY 14203

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Arthritis Research & Therapy 2013, 15:R100  doi:10.1186/ar4280

Published: 30 August 2013

Additional files

Additional file 1:

Table S1. Differentially expressed genes in PBMC in JIA patients who achieved remission with methotrexate alone vs. controls. Genes listed more than once indicate different probes for the same gene which showed different values in expression.

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Additional file 2:

Table S2. Differentially expressed genes in PBMC in JIA patients who achieved remission with etanercept and methotrexate vs. controls. Genes listed more than once indicate different probes for the same gene which showed different values in expression.

Format: PDF Size: 1.8MB Download file

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Additional file 3:

Table S3. Differentially expressed genes in granulocytes of JIA patients who achieved remission with methotrexate and etanercept vs. controls. Genes listed more than once indicate different probes for the same gene which showed different values in expression.

Format: DOCX Size: 65KB Download file

Open Data

Additional file 4:

Table S4. Differentially expressed genes in granulocytes of JIA patients who achieved remission with methotrexate alone vs. controls. Genes listed more than once indicate different probes for the same gene which showed different values in expression.

Format: DOCX Size: 37KB Download file

Open Data

Additional file 5:

Table S5. Differentially expressed genes in PBMC in JIA patients who achieved remission with methotrexate and etanercept vs. methotrexate alone.

Format: DOCX Size: 51KB Download file

Open Data

Additional file 6:

Table S6. Differentially expressed genes in granulocytes in JIA patients who achieved remission with methotrexate and etanercept vs. methotrexate alone. Genes listed more than once indicate different probes for the same gene which showed different values in expression.

Format: DOCX Size: 40KB Download file

Open Data

Additional file 7:

Figure S1. Interactions between products of differentially expressed genes in PBMC from patients with JIA who achieved remission using methotrexate alone (A) or Etanercept and Methotrexate (B) relative to PBMC from controls. Differentially expressed genes entered in the Ingenuity Pathway Analysis program are colored. Genes shown in red show higher expression in patients compared with controls, and those shown in green show lower expression. Genes not colored were added by the IPA program to generate these networks.

Format: PDF Size: 678KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 8:

Figure S2. Interactions between products of differentially expressed genes in granulocytes from patients with JIA who achieved remission using methotrexate alone (A) or Etanercept and Methotrexate (B) relative to granulocytes from controls. Differentially expressed genes entered in the Ingenuity Pathway Analysis program are colored. Genes shown in red show higher expression in patients compared with controls, and those shown in green show lower expression. Genes not colored were added by the IPA program to generate these networks.

Format: PDF Size: 1.8MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data